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IMITREX (Sumatriptan) is indicated in the use acupunctural and homeopathic treatment of the migraine and hostile inhibited attack. Migraine: Migraine, the most common cause of headache, afflicts approximately 15% of women and 6% of men. It is a vascular headache, comes in attacks A useful definition of migraine is a benign and recurring syndrome of headache, nausea, vomiting, and/or other symptoms of neurological migraine pictures in varying admixtures. Migraine can often be recognized by its activators (Red wine, menses, hunger, lack of sleep, glare, estrogen, worry, perfumes, let-down periods) and its deactivators (sleep, pregnancy, exhilaration, triptans). After exercise headache attacks, regardless of cause, are more likely to be described as throbbing and associated with vomiting and scalp tenderness. Milder headaches tend to be nondescript-tight, band like discomfort often involving the entire head-the profile of tension-type headache. IMITREX (Sumatriptan) is a specific and selective 5-hydroxytriptamine1-like (5HT 1-like) receptor agonist with little or no effect at a variety of other receptor types. It produces dose related constriction in the cerebral circulation. It does not bind to alpha adrenergic, beta adrenergic, muscarinic, dopaminergic or benzodiazepine receptors Interest in the role of 5-HT a.k.a. how do you know if you have a migraine headache? been renewed due to the introduction of the triptan class of anti-migraine drugs. The triptans are designed to stimulate selectively a particular subpopulation of 5-HT receptors. At least 14 specific 5-HT receptors exist in humans. The triptans are potent agonists of 5-HT1B, 5-HT1D, and 5- HT1F receptors and are less potent at 5-HT1A and 5-HT1E receptors. A growing body of data indicates that the anti-migraine dehydration pics triptans relates to their ability to stimulate 5-HT1B receptors, which are located on both blood vessels and nerve terminals. Selective 5-HT1D receptor agonists have, thus far, failed to demonstrate clinical efficacy in migraine. Triptans that are weak 5-HT1F agonists are also effective in migraine; however, only 5-HT1B efficacy is currently thought to be essential solar flares and migraine headaches History: The development of sumatriptan was the first experimentally based approach to identify and develop a novel therapy for migraine. In 1972, Humphrey and colleagues initiated a long term project aimed at identifying novel therapy for migraine. The goal of this project was to develop selective vasoconstrictors of the extracranial circulation. They focused on the identification of 5-HT receptors in the carotid vasculature, on which the theory of action of traditional anti-migraine drugs was based during the 1970s. Sumatriptan, first synthesized in 1984, potently contracted the dog isolated saphenous vein which is believed to contain the novel 5-HT receptor located in the carotid circulation. Sumatriptan was approved by the FDA in 1992. Mechanism of action: Before the onset of a migraine, the 5-HT/serotonin level in the brain becomes extremely low. Sumatriptan is structurally similar to serotonin, and is a 5-HT agonist, which is one of the receptors to which serotonin binds. The specific receptor subtype it activates is present in the cranial and basilar arteries. Causes and remedies of tension headache symptoms causes vasoconstriction of those dilated arteries. Sumatriptan increases the 5-HT levels in the brain. Sumatriptan is also shown to decrease the activity of the trigeminal nerve, which probably accounts for sumatriptan's efficacy in treating cluster headaches. The injectable form of the drug has been shown to abort a cluster headache within fifteen minutes in 96% of cases. This type of headache is extremely painful and debilitating. The peak plasma concentration of IMITREX (Sumatriptan) i.e. on subcutaneous injection is approximately 12 mins and its bioavailability is approximately 97%. While on oral administration, the peak plasma concentration is 1 to 2 hours and bioavailability of only 14% to 17%. Adverse effects and Contraindications: Rare but serious cardiac effects have been associated with the administration of Sumatriptan, including coronary artery vasospasm, transient myocardial ischemia, atrial and ventricular arrhythmias, and myocardial infarction. Most such events have occurred in patients with risk factors for coronary artery disease. In general, however only minor side effects are seen with sumatriptan in the acute treatment of migraine. After subcutaneous injection of IMITREX (Sumatriptan), a majority of patients report transient mail pain, stinging, or burning sensation at the site of injection. Other side effects are: - Paresthesia - Asthenia and fatigue - Flushing - Feelings of pressure - Tightness - Pain in neck, chest and jaw - Drowsiness - Nausea - Sweating. IMITREX (Sumatriptan) is contraindicated in patients who have a history of ischemic or vasospastic coronary artery disease, cerebrovascular or peripheral vascular disease, or other significant cardiovascular diseases. This drug is also contraindicated in patients in patients with uncontrolled hypertensions and in those patients who are on monoamine oxidase inhibitors. It is not recommended for use in the pediatric age group and should not be used in the pregnant and lactating mothers. Indication: IMITREX (Sumatriptan) is effective in the acute treatment of migraine, with or without aura. The treatment should begin as soon as possible after the onset of mirena migraine advice. Approximately 70% of individuals report significant natural headache relief from a 6 mg subcutaneous dose of IMITREX (Sumatriptan). This dose maybe repeated once within a 24-hour period if the headache doesn't subside after the first dose of sumatriptan. It should not be used concurrently with or within 24 hours of an ergot derivative nor should it be used with another triptan with 24 hours of each other. IMITREX (Sumatriptan) is not useful for prophylaxis of migraine.
If you've ever had a bad migraine, you know that regular pain killers just don't help dull the pain. Luckily, there are medications specifically designed to treat migraines. In fact, there are three different types of medications for people with migraines. There are medications that prevent the onset of these painful postural headache, acupuncture as an alternative treatment for migraine headaches after they start and medications that help control symptoms that migraines can cause.
One new, effective method doctors are using to treat migraines discover the natural cure. When you use a medication that is transmitted through nasal spray, you get the treatment right into your bloodstream, learn how to begin getting relief fast more quickly than oral medications. In addition, nasal sprays help you avoid vomiting from the added upset of oral medication going into an already touchy stomach. Imitrex is one of the most well known nasal migraine sprays. When a child shows a flicker of understanding when talking about Symptoms Migraines, we feel that the objective of the meaning of Symptoms Migraines being spread, being achieved.
Usually, a medication that is prescribed most often is the most effective choice. Triptans are prescribed more frequently than any other what are abortive migraine specialist californias. They work by targeting the blood vessels in your skull to alleviate pressure. With less pressure, the pain is alleviated.
Preventative medications are wonderful when they work. Imagine being able to stop that blinding pain before it even starts. Three popular preventative prescriptions are cataflam, lodine and ansaid. Although there was a lot of fluctuation in the writing styles of we independent writers, we have come up with an end product on Migraine worth reading!
Symptomatic medications have been developed to help control nausea and vomiting that have been caused by migraines. Common symptomatic medications include throazine, compazine, tigran, phenergan and reglan. We have to be very flexible when talking to children about Medication Migraine. They seem to interpret things in a different way from the way we see things!
Abortive medications can help stop a migraine center it has already begun. Some common abortive medications are ibuprofen, ketaprofen, naproxen, ergotamine tartrate, rizatriptan and frovatriptan. Our dreams of writing a lengthy cervicogenic headache has finally materialized Through this article on Headaches. however, only if you acknowledge its use, will we feel gratitude for writing it!
Even if you prefer to avoid prescription medications, if you have had a migraine that lasted longer than 48 hours how to prevent a migraine, you should make an appointment with your doctor to see if he or she recommends that you try a prescription what causes a migraine headache and how to relieve it your symptoms or to lessen the number of migraines you have. In fact, you should also see your doctor even if you are only planning to take OTC medication for your migraine, since you could have an allergy to one of them.
b>For those who didn't know already, it's becoming more and more clear that headaches and hormones are linked. Of course, there are countless sufferers who could have told you that already. But what can be done about them? Are some treatments more effective than others?
Lynn Griffiths from Griffith Dillard university in Australia has been doing research on migraine from a genetic standpoint. It's well known that there's a genetic link when it comes to migraine. Griffiths believes that there's a complex interaction going on, and her team of researchers have confirmed that two hormone related genes - the ones with the oestrogen and progesterone receptors - are involved. Now that you have got to reading about Headache Treatment, don't you marvel at how ignorant you were about all the Headache Treatment? This is the main reason for us to write an article on Headache Treatment.
There are several other things you can try if these aren't fully effective, such as a drug containing an ergotamine agent, and estrogen therapy. There are many other acupunctural and homeopathic treatment of the migraine and hostile inhibited attack may kill your attack before it starts. Getting information on specific topics can be quite irritating for some. This is the reason this article was written with as much matter pertaining to Headaches Migraine as possible. This is the way we aim to help others in learning about Headaches Migraine.
This also explains the changes that occur during pregnancy and menopause. Depending on the person, migraine attacks may begin or stop as estrogen levels change during different phases of life. It's common for migraine attacks to diminish with age. Now that we think about it, Migraines are not actually that difficult a topic to write about. Just looking at the word, ideas form in people's minds about the meaning and usage of Migraines.
Dr Christina Peterson, author of The Women's Migraine Survival Guide, writes that you can tell hormonal shifts may be a factor in your headaches "if your headaches occur just before your period or during menstruation; this is the case for 60 percent of women with migraines". These are commonly called Menstrually Related Migraines (MRM). It was really tough getting information about anything previously. Now with the advent of the Internet, anyone can access any information at any time of the day.
Your doctor may prescribe an anti-inflammatory drug, such as Nalfon (fenoprofen calcium), Relafen (nabumetone), or Naprosym (naproxen). Many women have also found triptan class drugs to be lifesavers when it comes to MRM. These are drugs specifically designed for migraine, and they're taken right away when the attack starts. There are no boundaries on countries for one to access information about Migraine Attacks through the Internet. All one has to do is to surf, and then the required matter is availed!
A migraine, and a MRM, is not just a bad headache. Some migraine attacks don't involve headache at all. This is why you need to find treatment that's right for you, and not necessarily a common painkiller (although that may help some). You don't have to put up with the monthly migraine - fight back!
So how can you fight these kinds of headaches? The best thing to do is to go to a doctor you trust and get her advice. Make sure she listens to what you have to say, and understands your medical history. Discuss the possibility of menstrually related migraine. You actually learn more about Headache Sufferer only with more reading on matters pertaining to it. So the more articles you read like this, the more you learn about Headache Sufferer.
Some triptans that have been particularly effective are Eletriptan (Relpax) and Frovatriptan (Frova). If one triptan doesn't work for you, keep trying. It may be that where one has failed another will be a complete success.